European Society for Magnetic Resonance in Medicine and Biology

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The pre-conference day on “Microstructural Imaging” explores cutting-edge techniques and applications in the field. Attendees will learn about advanced numerical simulation for modelling complex tissue microenvironments, as well as diffusion MRI for probing tissue microstructure through water diffusion patterns. The program also covers relaxation MRI for assessing tissue composition based on T1/T2 properties and quantitative susceptibility mapping (QSM) for studying magnetic tissue properties. Additionally, the workshop highlights high-resolution microscopy integration with MRI, emerging insights into neuro-fluids (cerebrospinal fluid dynamics and glymphatic system function), and innovative diffusion functional MRI (dfMRI) for mapping neural activity via diffusion-based contrasts. Through lectures, and an hands-on session, and interdisciplinary discussions, participants will gain a deeper understanding of how these methods enhance the study of tissue microstructure in health and disease.

09:00 – Opening

09:15 – Diffusion Microstructure Andrada Ianus – King’s College London, UK

09:40 – Principles of Relaxation and QSM Valerij Kiselev – University Hospital Freiburg, Germany

10:05 – Dealing with Motion in Body Diffusion Imaging Dimitrios Karampinos – École Polytechnique Fédérale de Lausanne, Switzerland

10:30 – Break

SESSION 2: SIMULATIONS

11:00 – Diffusion NMR in Porous Media: Advances and Perspectives Denis Grebenkov – CNRS École Polytechnique, France

11:25 – Virtual Tissues, Real Insights: Simulating Biological Microstructure for MRI Mariam Andersson – Danish Research Center for Magnetic Resonance, Denmark

11:50 – Simulating Diffusion and Perfusion in Microvasculature Elizabeth Powell – University College London, UK

LUNCH SYMPOSIUM SPONSORED BY OLEA MEDICAL

12:15 – Advanced Diffusion and Tractography in OleaSphere: A Gateway to Microstructural ImagingStefano Casagranda – Olea Medical

ROUND TABLE DISCUSSION – QUALITATIVE VS QUANTITATIVE?

13:15 A round table discussion from three different points of view Petra S. Hüppi, Geneva University and University Hospital, Switzerland & Jan-Patrick Stellamn – Aix-Marseille University, France & Filip Szczepankiewicz – Lund University, Sweden & Maria Eugenia Caligiuri, University of Catanzaro, Italy & Thomas Troalen– Siemens Healthineers, France

Moderated by: Nikola Stikov, Montreal Polytechnic University, Canada

SESSION 3: HANDS-ON ON DATA HANDLING AND PREPROCESSING

14:00 – Data handling, pre-processing and pipelining Oscar Esteban – HES-SO Wallis, Switzerland & Demian Wassermann – INRIA Saclay, France

15:30 – Break and POSTER SESSION #1

SESSION 4: EMERGING METHODS IN MICROSTRUCTURE IMAGING

16:00 – Microstructural diffusion MRI as a functional contrast complementary to BOLD Ileana Jelescu – Lausanne University Hospital, Switzerland
16:25- Seismology of the Brain Jaco JM Zwanenburg – UMC Utrecht, Netherlands
16:50 – Emerging AI Methods for Parameter Estimation Maëliss Jallais – Cardiff University, UK
17:15 – Concluding remarks
17:30 – POSTER SESSION #2

FILL THIS FORM TO CONFIRM PARTICIPATION

ORGANIZING COMMITTEE : Elda Fischi-Gomez (Chair), Emmanuel Caruyer, Marco Palonmbo, Marco Pizzolato, Emma Thomson, Chantal Tax

ESMRMB-GREC Meeting: Scientific Program

Meeting venue:  
Palais du Pharo Centre de Congrès – 58 boulevard Charles Livon – 13007 MARSEILLE

ESMRMB office: office@esmrmb.org

Certification: Participants will receive a certificate of attendance

Enrolment: The meeting in presence is designed for scientists and consultants.

Scientific Program Chair: Eliana Gianolio, Turin (IT)

After an extraordinary year of achievements, it is our pleasure to invite you to the 10th ESMRMB-GREC meeting, to be held in Marseille, France, during the ESMRMB Pre-Congress day.

Introduction:
This meeting is designed as a unique context aimed at sharing ideas and data on MRI contrast agents research and possible gadolinium toxicity after the administration of gadolinium-based contrast agents (GBCA). Joint international efforts will remain essential to optimize diagnostic efficacy and improve patient safety in MR imaging. Since 2016, the ESMRMB-GREC has adapted the contents of the discussion to current hot topics and has continuously improved its influence on the clinical and pre-clinical role of gadolinium-based contrast agents.
This 10th GREC meeting will cover topics related to the four missions of the group: 1. Clinical indications and optimal use of GBCA-enhanced MRI; 2. The chemistry of improved MRI contrast agents; 3. Optimizing contrast-enhanced MRI, including Artificial Intelligence; 4. Emissions and ecotoxicological effects of GBCA in the marine environment.
As a working group of experts with multidisciplinary background, we support the MR community with continuous education, information and scientific updates on the use and clinical applications of GBCA.

Objectives:

  • To share evidence-based state-of-the-art information on specific hot and emerging topics in GBCA-enhanced MR imaging
  • To promote the dissemination of knowledge by means of papers to be published on behalf of the ESMRMB-GREC working group
  • To discuss on research activities and research funding opportunities

Date: 8th October 2025

08:30-08.35         Welcome and practical meeting issues
Eliana Gianolio, IT, Carlo C. Quattrocchi, IT,  Aart J. van der Molen, NL

Session 1                 GREC Business Meeting 2025
                                      Moderator: Carlo C. Quattrocchi, IT

08.35-08.45             Mission Group 1: Achievements 2024-2025 and new ideas (Fabio Doniselli, IT)
08.45-08.55             Mission Group 2-4: Achievements 2024-2025 and new ideas (Eliana Gianolio, IT)

Mission 1                Clinical Indications and Optimal Use of GBCA-enhanced MRI
Session 2                 Moderator: Fabio Doniselli, IT

08:55-09:10            Glymphatic system: Intrathecal or intravenous GBCA administration? – Geir Ringstad (Oslo,NO)
09:10-09:25            New MRI techniques to assess the glymphatic system – Matthijs van Osch (Leiden, NL)
09.25-09.40            Pre-load and 2nd bolus injections of GBCA in Neuroradiology – Fabio Doniselli (Milan, IT)

09.40-09:55                                                               Discussion

Mission 3                Optimizing Contrast-Enhanced MR Imaging: Advances in GBCA
Session 3                 Moderator: Aart J. van der Molen, NL

09.55-10:10            Deep learning synthetic MRI in neuro-oncology – Elisa Moya-Sáez (Valladolid, ES)
10:10-10:25            Artificial Intelligence for contrast-free cardiac MRI – Stefan Piechnik (Oxford, UK)

10.25-10.30                                                                Discussion

10.30- 11:00                                                                           Coffee break

Mission 3                Optimizing Contrast-Enhanced MR Imaging: Advances in GBCA
Session 3                 Moderator: Aart J. van der Molen, NL

11:00-11:15            Peripheral Nervous System Integrity After GBCA Exposure: A Preclinical Toxicity and Reversibility Study in Non-Human Primates – Simona Bussi (Bracco Imaging)
11:15-11:30           MRI Beyond Gadolinium: Manganese as the Next Frontier – Sigrid Fossheim (GE Healthcare)
11.30-12.00           Gadoquatrane, a novel next-generation low dose macrocyclic GBCA: Features and Results from preclinical and clinical studies- Petra Palkowitsch and Hubertus Pietsch (Bayer)
12.00-12.15           Evaluating Gadolinium Deposition in Bone Tissues after Contrast-Enhanced MRI: A Comprehensive Review – Nathalie Fretellier (Guerbet)

12.15-12.45                                                                  Discussion

12.45-14:00                                                            Lunch time and open discussion

Mission 3                Dose Reduction in Contrast-Enhanced MR Imaging
Session 4                 Moderator: Juan Hernandez Tamames, NL

14:00-14:15            GBCA use in Cardiovascular MR: Amsterdam Experience – Ilona Dekkers (Amsterdam, NL)
14.15-14.30            Enhancing Image Quality with DL in Rapid Post-Contrast Studies – Christiana Araujo (Siemens Healthineers)
14:30-14:45            Contrast Agent-Specific Parameter Optimization for T1-weighted Fast Spoiled Gradient Echo Imaging – Dimosthenis Gkotsis (GE Healthcare)
14:45-15:00            Practical insights into the optimization of low/non-contrast MRI acquisition – Marc Kouwenhoven (Philips)

15:00-15:30                                                                     Discussion

15:30- 16:00                                                                           Coffee break

Mission 4                Emissions and Ecotoxicological Effects of GBCA in the Aqueous Environment
Session 5                 Moderator: Gerard Stroomberg, NL

16:00-16:15            Contrast Catch: Collecting GBCA from patient urine in hospitals – Mathijs Maris (Roosendaal, NL)
16:15-16:30            The PREMIER project: Improving the environmental risk assessment of pharmaceuticals – Ad Ragas (Nijmegen, NL)
16.30-16:45           Impact of gadolinium on marine and coastal systems – Rosa Freitas (Aveiro, PT)
16:45-17:00           Speciation analysis of established and emerging GBCAs in German Rivers- Mathis Athmer (Münster, GE)

17.00-17.15                                                                      Discussion

Dessert                    ESMRMB-GREC meets ….
Session 6                 Moderator: Aart van der Molen, NL

17:15-17:30           ESMRMB-GREC meets ESGAR: Recommended use of liver-specific MR contrast agents in MRI of the liver – Maxime Ronot (Paris, FR)
17:30-17:45           ESMRMB-GREC meets ESHNR: Contrast-enhanced MRI in vestibular diseases: When is GBCA making the difference?  – Aina Venkatasamy (Strasbourg, FR)

18.00-18.15                                                                      Discussion & Adjourn

Date: 9th October 2025

10:30- 11:00                                                                           Coffee break

Mission 2                The Chemistry of Improved MRI Contrast Agents
Session 6                 Moderator: Eliana Gianolio, IT

11:00-11:15            Efficient Recovery of Gadolinium from Contaminated Waters using Manganese Ferrite Nanoparticles – Eduarda Pereira (Aveiro, PT)
11:15-11.30            Manganese Complexes as Alternatives to Gd-based Agents – Eva Toth (Orleans, FR)
11:30-11:45            High relaxivity GBCA: Gadopiclenol & Gadoquatrane – Carlo Mallio (Rome, IT)

11.45-12.00                                                                      Discussion

Mission 2                The Chemistry of Improved MRI Contrast Agents: Targeted MRI contrast agents
Session 7                 Moderator: Alkystis Phinikaridou, UK

12:00-12:15            Chemistry of targeted Gd-agents – Sara Lacerda (Orléans, FR)
12:15-12.30            Preclinical applications of targeted Gd-agents : Alkystis Phinikaridou (London, UK)
12:30-12:45            The clinical need of targeted Gd agents to detect fibrosis across organs — a clinical   perspective– Maxime Gauberti (Caen, FR)

12.45-13.00                                                                  Discussion

13.00-13.30         Closing Keynote lecture: Reducing contrast agent use for neuro-oncology – Marion Smits (Rotterdam, NL)

13.30-13.45             Adjourn of GREC 2025
Enjoy 2025 ESMRMB congress
See you next year at the 11th ESMRMB-GREC 2026 in Girona, Spain

ESMRMB-GREC Chairs
Carlo C. Quattrocchi, IT – carlo.quattrocchi@unitn.it
Aart J. van der Molen, NL – a.j.van_der_molen@lumc.nl

ESMRMB-GREC Senior Faculty
Eliana Gianolio, IT
Alex Rovira, ES
Ilona Dekkers, NL
Juan Hernandez Tamames, NL
Gerard Stroomberg, NL
Ad Ragas, NL
Carlo A. Mallio, IT
Douraied Ben Salem, F
Geir Ringstad, NO
Johannes Haubold, DE
Olivier Clement, FR
Alkystis Phinikaridou, UK
Eduarda Pereira, PT
Rosa Freitas, PT
Eva Toth, FR
Maxime Gauberti, FR
Matthijs van Osch, NL
Angelina Pieters, NL
Stefan Piechnik, UK

ESMRMB-GREC Junior Faculty
Fabio Doniselli, IT
Lorenzo Palagi, IT
Sara Lacerda, FR
Elisa Moya-Saéz, ES
Mathis Athmer, GE

ESMRMB-GREC Industry Delegates
Laura Schöckel – Bayer AG
Hubertus Pietsch – Bayer AG
Petra Palkowitsch – Bayer AG
Hassan Khater – Bayer AG
Alberto Spinazzi – Bracco
Antonella Filippone – Bracco
Simona Bussi- Bracco
Sonia Colombo-Bracco
Sigrid Fossheim – GE HealthCare
Marion Uetwiller – GE HealthCare
Sarah Catoen – Guerbet
Jean-Sebastien Raynaud – Guerbet
Eric Lancelot – Guerbet
Nathalie Fretellier- Guerbet
Marc Kouwenhoven – Philips
Cristiana Araujo – Siemens
Dimosthenis Gkotsis – GE Healthcare MRI
Mathijs Maris – Zereau

Institutional Scientific Patronage from ESMRMB

Unconditional support from Bayer AG, Bracco, GE Healthcare and Guerbet

All coffee breaks and lunch are included in the price!
The first 25 junior registrants under 35 will receive reimbursement for the precongress and ESMRMB main congress worth 130 Euros!

Register for GliMR
(note if you are a junior while filling in)

Pay for the First GliMR Congress via the ESMRMB 2025 registration portal

Time (CET)Programme pointSpeakers
09.00-09.05Casual walk-in
09.05-09.10Opening welcomeEsther Warnert (NL),
Chair
09.10-09.40Power Pitches of GliMR Task Force
leads presenting their activities
The Task Force Leads
09.45-10.30Key topic 1: Tumoral microenvironments: what to see and how to interpret
(Use case: tumor progression)
Rui Simoes (PT) Tom Booth (UK) Harish Poptani (UK)

Coffee Break 1

11.05-12.35Hands-on workshop on individualised
perfusion imaging in brain tumors
Cercare

Lunch break

13.30-14.00

Keynote lecture:

“Imaging follow-up in IDH-mutated glioma patients: from tumor kinetics to brain plasticity”.

Emmanuel Mandonnet (FR)
14.00-14.45Key Topic 2: What is going on here?
My weirdest case.
In this format, a panel of experts and the audience will try to solve anomalies in cases, data, statistics and images. Having mystery cases or data? Bring it in to this clinic!
Send your case or data issue to:
v.c.w.keil@amsterdamumc.nl
Panel of four clinical and
technological experts:
Gilbert Hangel (AU) Patricia Clement (BE) Rita Nunes (PT)
Albert Pons-Escoda (ES) audience
Johannes Slotboom (CH) Esin Öztürk Isik (TR) audience
14.45-15.30Key topic 3: IDH mutation prediction
– Where are we now?
The clinical and the technological perspective with group discussion
 

Coffee Break 2

16.00-16.45

Break-out Sessions of the Task forces and poster walk for project abstracts

Get to know the GliMR task forces and their projects for European glioma imaging better. Get involved
– or present a poster with an intended project at the project
poster wall.

TF 1: Advanced Imaging TF 2: Preclinical Imaging TF 3: AI
TF5: Clinical Implementation TF 8: Science Communication
16.45-17.00Closing remarksEsther Warnert (NL),
Chair

GliMR also has a main ESMRMB meeting session!

Qualify for the Young Investigator Award by sending in an abstract until September 1 to: v.c.w.keil@amsterdamumc.nl

Present your work on technological solutions for brain tumor imaging problems during the main meeting GliMR special topic session!

Step into the critical world of MRI safety with “A Journey Through Practical MRI Safety.” MRI is indispensable, but its power demands deep safety understanding. This seminar equips you with essential knowledge, from the basics of static, RF, and gradient magnetic fields, to crucial considerations like B1+rms, SAR, and SED. A highlight is our interactive case review on implant assessments, offering invaluable real-world insights. Enhance your expertise and contribute to a safer MRI practice—safeguarding lives and maintaining the integrity of this life-saving modality is paramount. Suitable for radiographers / MRI technologists, radiologists, researchers, and all looking to update or refresh their MRI safety knowledge.

Moderators: Frank Zarb (Msida/MT), Jonathan McNulty (Dublin/IE)

  • 13:15 Workshop Introduction / the ECSO MRI Project ……….Jonathan McNulty (Dublin/IE)
  • 13:30 The Basics of MRI Safety: The Static Magnetic Field .………Allison McGee (Dublin/IE)
  • 14:00 The Basics of MRI Safety: The Radiofrequency Magnetic Field ………. Andrea Cradock (Dublin/IE)
  • 14:30 The Basics of MRI Safety: The Gradient Magnetic Field ………. Vitor Silva (Porto/PT)
  • 15:00 B1+rms, SAR, and SED Considerations ………. Gilles De Moor (Brussels/BE)
  • 15:30 Coffee Break
  • 16:00 What you need to consider in the assessments of implants: An interactive case review session ………. Andrea Cradock (Dublin/IE), Joanne Grehan (Dublin/IE)
  • 17:00 Questions 
  • 17:15 Close