ESMRMB-GREC Meeting: Scientific Program

Meeting venue:
Palais du Pharo Centre de Congrès – 58 boulevard Charles Livon – 13007 MARSEILLE

ESMRMB office: office@esmrmb.org

Certification: Participants will receive a certificate of attendance

Enrolment: The meeting in presence is designed for scientists and consultants.

Scientific Program Chair: Eliana Gianolio, Turin (IT)

After an extraordinary year of achievements, it is our pleasure to invite you to the 10th ESMRMB-GREC meeting, to be held in Marseille, France, during the ESMRMB Pre-Congress day.

Introduction:
This meeting is designed as a unique context aimed at sharing ideas and data on MRI contrast agents research and possible gadolinium toxicity after the administration of gadolinium-based contrast agents (GBCA). Joint international efforts will remain essential to optimize diagnostic efficacy and improve patient safety in MR imaging. Since 2016, the ESMRMB-GREC has adapted the contents of the discussion to current hot topics and has continuously improved its influence on the clinical and pre-clinical role of gadolinium-based contrast agents.
This 10th GREC meeting will cover topics related to the four missions of the group: 1. Clinical indications and optimal use of GBCA-enhanced MRI; 2. The chemistry of improved MRI contrast agents; 3. Optimizing contrast-enhanced MRI, including Artificial Intelligence; 4. Emissions and ecotoxicological effects of GBCA in the marine environment.
As a working group of experts with multidisciplinary background, we support the MR community with continuous education, information and scientific updates on the use and clinical applications of GBCA.

Objectives:

• To share evidence-based state-of-the-art information on specific hot and emerging topics in GBCA-enhanced MR imaging
• To promote the dissemination of knowledge by means of papers to be published on behalf of the ESMRMB-GREC working group
• To discuss on research activities and research funding opportunities

Date: 8th October 2025

08:30-08.35 – Welcome and practical meeting issues
Eliana Gianolio, IT, Carlo C. Quattrocchi, IT, Aart J. van der Molen, NL

Session 1 GREC Business Meeting 2025
Moderator: Carlo C. Quattrocchi, IT

08.35-08.45 – Mission Group 1: Achievements 2024-2025 and new ideas (Fabio Doniselli, IT)
08.45-08.55 – Mission Group 2-4: Achievements 2024-2025 and new ideas (Eliana Gianolio, IT)

Mission 1 – Clinical Indications and Optimal Use of GBCA-enhanced MRI
Session 2 – Moderator: Angelina Pieters, NL

08:55-09:10 – Glymphatic system: Intrathecal or intravenous GBCA administration? – Geir Ringstad (Oslo,NO)
09:10-09:25 – New MRI techniques to assess the glymphatic system – Matthijs van Osch (Leiden, NL)
09.25-09.40 Pre-load and 2nd bolus injections of GBCA in Neuroradiology – Fabio Doniselli (Milan, IT)

09.40-09:55 – Discussion

Mission 3 – Optimizing Contrast-Enhanced MR Imaging: Advances in GBCA
Session 3 – Moderator: Aart J. van der Molen, NL

09.55-10:10 – Deep learning synthetic MRI in neuro-oncology – Elisa Moya-Sáez (Valladolid, ES)
10:10-10:25 – Artificial Intelligence for contrast-free cardiac MRI – Stefan Piechnik (Oxford, UK)

10.25-10.30  – Discussion

                                     
10.30- 11:00 – Coffee break

Mission 3 – Optimizing Contrast-Enhanced MR Imaging: Advances in GBCA
Session 3 – Moderator: Aart J. van der Molen, NL

11:00-11:15 – Peripheral Nervous System Integrity After GBCA Exposure: A Preclinical Toxicity and Reversibility Study in Non-Human Primates – Simona Bussi (Bracco Imaging)
11:15-11:30 – Beyond Gadolinium: Environmental and Geopolitical Drivers of Innovation in MRI- Anand Bherwani (GE Healthcare)
11.30-11-45 – Navigating the Green Frontier: The Case for Manganese and Non-Gd Alternatives – Anand Bherwani (GE Healthcare)
11:45-12:15 – Gadoquatrane, a novel next-generation low dose macrocyclic GBCA: Features and Results from preclinical and clinical studies- Petra Palkowitsch and Hubertus Pietsch (Bayer)
12:15-12.30 – Evaluating Gadolinium Deposition in Bone Tissues after Contrast-Enhanced MRI: A Comprehensive Review- Nathalie Fretellier (Guerbet)

12.30-13.00 – Discussion

13.00-14:00 – Lunch time and open discussion

Mission 3 – Dose Reduction in Contrast-Enhanced MR Imaging
Session 4 – Moderator: Juan Hernandez Tamames, NL

14:00-14:15 – GBCA use in Cardiovascular MR: Amsterdam Experience – Ilona Dekkers (Amsterdam, NL)
14.15-14.30 – Enhancing Image Quality with DL in Rapid Post-Contrast Studies – Christiana Araujo (Siemens Healthineers)
14:30-14:45 – Contrast Agent-Specific Parameter Optimization for T1-weighted Fast Spoiled Gradient Echo Imaging – Dimosthenis Gkotsis (GE Healthcare)
14:45-15:00 – Practical insights into the optimization of low/non-contrast MRI acquisition – Maarten Versluis (Philips)

15:00-15:30 – Discussion

15:30- 16:00 – Coffee break

Mission 4 – Emissions and Ecotoxicological Effects of GBCA in the Aqueous Environment
Session 5 – Moderator: Gerard Stroomberg, NL

16:00-16:15 – Contrast Catch: Collecting GBCA from patient urine in hospitals – Mathijs Maris (Roosendaal, NL)
16:15-16:30 – The PREMIER project: Improving the environmental risk assessment of pharmaceuticals – Ad Ragas (Nijmegen, NL)
16.30-16:45 – Impact of gadolinium on marine and coastal systems – Rosa Freitas (Aveiro, PT)
16:45-17:00 – Speciation analysis of established and emerging GBCAs in German Rivers- Mathis Athmer (Münster, GE)

17.00-17.15 – Discussion

Dessert – ESMRMB-GREC meets ….
Session 6 – Moderator: Aart van der Molen, NL

17:15-17:30 – ESMRMB-GREC meets ESGAR: Recommended use of liver-specific MR contrast agents in MRI of the liver – Maxime Ronot (Paris, FR)
17:30-17:45 – ESMRMB-GREC meets ESHNR: Contrast-enhanced MRI in vestibular diseases: When is GBCA making the difference?  – Aina Venkatasamy (Strasbourg, FR)
17.45-18.00 – ESMRMB-GREC meets ISMRM: The new ISMRM Study Group on MR contrast agents – Giles Roditi (Glasgow, UK)

18.00-18.15 – Discussion & Adjourn

Date: 9th October 2025

10:30- 11:00 – Coffee break

Mission 2 – The Chemistry of Improved MRI Contrast Agents
Session 6 – Moderator: Eliana Gianolio, IT

11:00-11:15 – Efficient Recovery of Gadolinium from Contaminated Waters using Manganese Ferrite Nanoparticles – Eduarda Pereira (Aveiro, PT)
11:15-11.30 – Manganese Complexes as Alternatives to Gd-based Agents – Eva Toth (Orleans, FR)
11:30-11:45 – High relaxivity GBCA: Gadopiclenol & Gadoquatrane – Carlo Mallio (Rome, IT)

11.45-12.00 – Discussion

Mission 2 – The Chemistry of Improved MRI Contrast Agents: Targeted MRI contrast agents
Session 7 – Moderator: Alkystis Phinikaridou, UK

12:00-12:15 – Chemistry of targeted Gd-agents – Sara Lacerda (Orléans, FR)
12:15-12.30 – Preclinical applications of targeted Gd-agents : Alkystis Phinikaridou (London, UK)
12:30-12:45 – The clinical need of targeted Gd agents to detect fibrosis across organs — a clinical perspective– Maxime Gauberti (Caen, FR)

12.45-13.00 – Discussion

13.00-13.30 – Closing Keynote lecture: Reducing contrast agent use for neuro-oncology – Marion Smits (Rotterdam, NL)

13.30-13.45 – Adjourn of GREC 2025
Enjoy 2025 ESMRMB congress
See you next year at the 11th ESMRMB-GREC 2026 in Girona, Spain

ESMRMB-GREC Chairs
Carlo C. Quattrocchi, IT – carlo.quattrocchi@unitn.it
Aart J. van der Molen, NL – a.j.van_der_molen@lumc.nl

Institutional Scientific Patronage from ESMRMB

Unconditional support from Bayer AG, Bracco, GE Healthcare and Guerbet